When my grandmother wanted to visit, and talked about staying at a "Best Western," I was against it. But when I saw the internet imageshttp://www.universitytowerhotel.com/ of this old Art-Deco style building, I changed my mind! It wasn't very expensive, though twice the price of a "Motel 6". For about $120/night, we got a view of the U-District, two queen-sized beds, free wireless internet, continental breakfast, and great service. It's a block away from 45th and University, near the Neptune Theater. There is a Tully's attached to it, and an upscale bar/banquet area in the basement. And the lobby is so cozy, you might not feel like leaving it.
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