I've been to Staples Center a few times for various events. It's a great structure with adequate parking within the building. The main negative thing is the area...it's downtown Los Angeles so there are a lot of scary people out and about at night after games. Also traffic is a nightmare...I was at the E3 Conference a few months ago and it took me thirty minutes to drive three blocks after the conference. So that is definitely a hassle.
Other than that it's a great place to check out the Lakers or any of the live events they have there constantly. Odds are you'll have to visit there if you want to see the big concerts in the Southern California area.
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