Econo Lodge is a basic, but usually quite reliable chain. The Natchez branch has a very convenient location on one of the main streets at the entrance of the town. The staff is invariably friendly and helpful. The complimentary breakfast is quite nice and all of the rooms that we've ever stayed in (so far 3) had a coffee maker, microwave and a fridge, so one could fix a quick meal easily. The hotel also offers complimentary wireless internet in the rooms as well as a computer for guests' use in the lobby area.
Although the hotel is not new, the rooms are well maintained and properly cleaned.
With a double room usually going for around $65, we found this to be a good value. Do not forget to ask for AAA, AARP or similar discount!