I have stayed at 4 Boston hotels. The room was a little smaller than most, and I could hear my neighbor's TV. It was quiet outside the window though because you are in a mini-neighborhood that was all just built. Many TV channels were not available, and the blanket was foam - not down (compared to Westin, Marriott, and The Charles). The maid came in room despite "do not disturb sign" while I was sleeping. The neighborhood feels a little dead. The room service menu is extremely overpriced. Some of the nearby restaurants on Mass Ave are kinda scary.
Pros: Near MIT, Very Clean, New
Cons: Weird Neighborhood, Expensive , Loud Heat / AC