The Sanford Meisner Theatre is located far west in Chelsea (when you step outside the theatre, you look at Chelsea Piers). The closest subways are the C & E at 23rd Street, but there is a bit of a walk to 11th Avenue where the theatre stands.
This is a 74 seat black box theatre. There are decently sized dressing rooms behind the stage. This is a good venue for a small show that can get an audience to head all the way west in order to see it.