The newly renovated Holiday Inn Express & Suites San Diego Otay Mesa welcomes you! This choice San Diego hotel is nestled in the heart of the Otay Mesa Industrial Business Park, a short drive from Downtown San Diego and less than a mile from beautiful Tijuana, Mexico. We offer a convenient suburban location near the Mattress Firm Amphitheatre, SeaWorld Aquatica, SeaWorld, the Chula Vista Olympic Training Park and the famous San Diego Zoo. Your family can learn about local history at the Cabrillo National Monument, the Air and Space Museum and the Maritime Museum, or visit us for fun annual events such as Comic Con. For some great bargains, check out Las Americas Premium Outlets with 125 outlet stores and 13 restaurants in a lovely outdoor setting, or try the Otay Town Center Mall, just four miles from our hotel. Business travelers will enjoy a stay at our San Diego hotel because of its convenient location near companies such as Toyota, Bose, Panasonic, Maxwell, Tyco, JVC, Siemens Medical and Samsung, each within six miles of our hotel in the Otay Mesa Industrial Park. The International Commercial Border Crossing is .25 miles away. The Brown Field Municipal Airport is three miles away. During your stay, enjoy a free hot breakfast, Fitness Center and outdoor pool. Check out our San Diego hotel room deals to start planning your trip today.. |IHG Rewards Club Members: Get better savings with YOUR RATE. Book hotels direct at holidayinnexpress.com for our lowest rates. You will not find these anywhere else. You may find yourself feeling particularly smart for choosing to stay at Holiday Inn Express. With nearly 1|800 locations worldwide|you will find comfortable|inviting accommodations with just the right mix of services and amenities all at very affordable rates. Stay Smart. Stay at Holiday Inn Express. With your comfort and convenience in mind: Still free. Now hot. Express Start Breakfast Bar Our breakfast bar now features hot entrees as well as our exclusive cinnamon rolls and Smart Roast Coffee. Simply Smart Bedding Collection Our bedding will have you waking up feeling refreshed and recharged.* Free High Speed Internet Access Enjoy free high-speed Internet access from your guest room. Our online concierge|eHost|is also available to assist with information about the hotel and the local area. Simply Smart Guest Bathroom Featuring the Stay Smart shower head by Kohler.* IHG Rewards Earn points toward free nights|airline miles|or merchandise on every qualifying stay. *Available at Holiday Inn Express hotels in North America only.