Experience Salem, Missouri with Our Hotel's Location Situated in the Ozarks, the Holiday Inn Express Salem Hotel boasts excellent amenities, as well as a great location near area businesses and attractions. As the leader in Salem, Missouri hotels, our property boasts more than 1,800 square feet of event space, as well as an on-site Business Center. Our great location also puts you near to area businesses, such as Walmart, Doe Run Recycling, the US Forest Service and the US Food Service. The Missouri Department of Conservation and Salem Memorial District Hospital are near our hotel's location, too. Salem is the perfect place to enjoy the outdoors: from hunting and fishing to canoeing and hiking, visitors can expect to experience a diverse range of activities.