Hiron's is a real Eugene conversation piece. The stores are packed with thousands of items, floor to ceiling (no kidding, here!)
The 18th Avenue location (next to Safeway) is a treasure trove of ornaments, stickers, gift items and all the usual drug store paraphernalia. If you need Tums or tampons, they've got those -- along with toothpaste and candy and bandaids. There's even a drive-through perscription pick-up area. The second store, on Franklin Blvd (near the UofO and next to PC Market of Choice) is more organized, but probably has just as many items.
The holiday season is thrilling at Hirons -- try to go several times, and especially check the after holiday sales. They carry varied and unusual items to trim a Christmas tree or toast in the New Year. Lots of affordable stocking stuffers along with some spendy gifts to exchange. In recent years, there are dozens of Halloween decorations for sale, and they keep things really fresh throughout the year. This is a great spot to check for birthday gifts for co-workers and friends.
Look for their hidden away "clearance" areas. These are great for bargain shoppers -- but check the condition before you buy. And, being close to UofO, there are generally lots of "Go Ducks" items.
Good spot for calendars & cards -- they also have fun bath stuff. The jewelry selection at 18th can be a nice surprize -- sometimes there are really wonderful, affordable things on display.