Welcome to the Holiday Inn Express & Suites Binghamton University-Vestal Located between Binghamton, Endicott and Johnson City, our Vestal, NY hotel is ideally situated in the southern tier of New York with easy access to Rte. 17, I-81 and I-88. The Holiday Inn Express & Suites, Vestal, NY hotel is near SUNY Binghamton University . Leisure travelers will love using our Vestal accommodations as a home base for sightseeing within the region. Whether visiting one of the local horse farms or taking advantage of the wealth of outdoor adventures nearby, there is plenty to do in Vestal. This hotel is within easy driving distance of Binghamton Senators Hockey, the Binghamton Zoo, Roberson Museum of Science Center & Link Planetarium and the Conklin Players Club.