Blanchard's is the biggest liquor, wine and beer store in Jamaica Plain. Their hours are reasonable, and the selection is good. The beer variety is pretty good, but not superb.
The store is fairly clean and sort of warehousing feeling. The staff are friendly enough but not always the most knowledgeable about wine. My favorite part though is the fairly regular beer tastings by vendors.
It's a good basic store. If you're looking for anything too obscure you may want to visit a different store, but for basics it is fine.