This NFP thrift store has pretty much anything you will ever need (and stuff you don't need, too!)
The store is laid out much better than many thrift stores - every section is clearly marked and well organized. Prices are cheaper than many other thrift stores (I'm looking at you Savers) and the selection is HUGE. You will find nothing there that is in poor condition.
On many holidays (President's Day for example) everything is 1/2 off and seniors get 15% off every Wednesday.
It is always busy though. Sometimes getting through the aisles is difficult. But all in all it's worth it. I've bought name brand clothes there (Lauren jeans for $3.97!), kitchen appliances (NIB Waffle Iron $2.97), books (most are .80C) - you name it, they have it. Their plus sized womens clothes selection is great!