If you're looking for the best touristy place to stay in Plymouth, this is it.
Every room is attractive, warm, and comfortable. The service is excellent, and it's very close to historic downtown Plymouth (walking distance) and the attached beaches (driving distance). Parking is free and abundant.
There is a hilariously tacky indoor pool with a life-size replica of the Mayflower. You have to see this thing to believe it; it's great. The pool is nice, too.
The hotel has strong ties to local tourism; for example, a ghost tour starts in the lobby (and at the end, they'll tell you that both the second and third floors are haunted).
For a nice place to stay at almost-reasonable prices, you won't be disappointed by the John Carver Inn.